After the Investec Champions Cup and EPCR Challenge Cup finals, the PREM returns for the penultimate round of the regular season.
There are five blockbuster matches pencilled in over the weekend, with plenty still to play for across the league.
Check on all the PREM team news, our predictions, how to watch and more below.
Friday
Bristol Bears v Bath
Prediction: Bath by 10
Bristol Bears: 15 Noah Heward, 14 Louis Rees-Zammit, 13 Matias Moroni, 12 Benhard Janse van Rensburg, 11 Kalaveti Ravouvou, 10 AJ MacGinty, 9 Harry Randall, 8 Santiago Grondona, 7 Fitz Harding (c), 6 Joe Owen, 5 Joe Batley, 4 James Dun, 3 George Kloska, 2 Harry Thacker, 1 Ellis Genge
Replacements: 16 Tomas Gwilliam, 17 Jake Woolmore, 18 Max Lahiff, 19 Jimmy Halliwell, 20 George Taylor, 21 Kieran Marmion, 22 Tom Jordan, 23 Jack Bates
Bath: 15 Santi Carreras, 14 Joe Cokanasiga, 13 Ollie Lawrence, 12 Max Ojomoh, 11 Henry Arundell, 10 Ciaran Donoghue, 9 Ben Spencer, 8 Sam Underhill, 7 Guy Pepper, 6 Ethan Staddon, 5 Charlie Ewels, 4 Ted Hill, 3 Thomas du Toit, 2 Kepueli Tuipulotu, 1 Beno Obano
Replacements: 16 Dan Frost, 17 Francois van Wyk, 18 Vilikesa Sela, 19 Ewan Richards, 20 Josh Bayliss, 21 Tom Carr-Smith, 22 Cameron Redpath, 23 Alfie Barbeary
Venue: Ashton Gate
Kick-off: 19:45 BST
Referee: Karl Dickson
Assistant Referees: Dan Jones, Jonathan Healy
TMO: Andrew Jackson
How to watch: Live on TNT Sports 1, HBO Max, TNT Sports Ultimate
Bristol v Bath team news: Benhard Janse van Rensburg to face off with snubbed England duo as Bears star makes long-awaited return
Saturday
Saracens v Harlequins
Prediction: Saracens by 12
Saracens: 15 Max Malins, 14 Noah Caluori, 13 Nick Tompkins, 12 Olly Hartley, 11 Tobias Elliott, 10 Fergus Burke, 9 Charlie Bracken, 8 Tom Willis, 7 Ben Earl, 6 Nick Isiekwe, 5 Hugh Tizard, 4 Maro Itoje (c), 3 Marcus Street, 2 Jamie George, 1 Eroni Mawi
Replacements: 16 Theo Dan, 17 Rhys Carre, 18 Alec Clarey, 19 Theo McFarland, 20 Nathan Michelow, 21 Ivan Van Zyl, 22 Owen Farrell, 23 Jack Bracken
Harlequins: 15 Jamie Benson, 14 Cameron Anderson, 13 Sean Kerr, 12 Bryn Bradley, 11 Cadan Murley, 10 Marcus Smith, 9 Will Porter, 8 Alex Dombrandt (c), 7 Jack Kenningham, 6 Chandler Cunningham-South, 5 Elliot Williams, 4 Zach Carr, 3 Pedro Delgado, 2 Sam Riley, 1 Will Hobson
Replacements: 16 Jack Musk, 17 Boris Wenger, 18 Ollie Streeter, 19 Jonny Green, 20 Seb Driscoll, 21 Will Evans, 22 Stu Townsend, 23 Cassius Cleaves
Venue: StoneX Stadium
Kick-off: 13:00 BST
Referee: Luke Pearce
Assistant Referees: Richard Gordon, Mike Woods
TMO: Dean Richards
How to watch: Live on TNT Sports 2, HBO Max, TNT Sports Ultimate
Want more from Planet Rugby? Add us as a preferred source on Google to your favourites list for world-class coverage you can trust.
Northampton Saints v Gloucester
Prediction: Northampton by 15
Northampton Saints: 15 George Furbank (c), 14 Tommy Freeman, 13 Tom Litchfield, 12 Rory Hutchinson, 11 George Hendy, 10 Fin Smith, 9 Archie McParland, 8 Callum Chick, 7 Henry Pollock, 6 Tom Pearson, 5 Ed Prowse, 4 Alex Coles, 3 Luke Green, 2 Robbie Smith, 1 Emmanuel Iyogun
Replacements: 16 Craig Wright, 17 Danilo Fischetti, 18 Elliot Millar Mills, 19 Tom Lockett, 20 Sam Graham, 21 Jonny Weimann, 22 Fraser Dingwall, 23 James Ramm
Gloucester: 15 Ben Redshaw, 14 Ollie Thorley, 13 Max Llewellyn, 12 Seb Atkinson (c), 11 Ben Loader, 10 Charlie Atkinson, 9 Caolan Englefield, 8 Will Trenholm, 7 James Venter, 6 Deian Gwynne, 5 Freddie Thomas, 4 Arthur Clark, 3 Afo Fasogbon, 2 Seb Blake, 1 Ciaran Knight
Replacements: 16 Jack Innard, 17 Dian Bleuler, 18 Nepo Laulala, 19 Matias Alemanno, 20 Jack Clement, 21 Mikey Austin, 22 Will Knight, 23 Josiah Edwards-Giraud
Venue: Franklin’s Gardens
Kick-off: 15:00 BST
Referee: Sara Cox
Assistant Referees: Matthew Carley, Wayne Falla
TMO: Hamish Smales
How to watch: Live on TNT Sports 2, HBO Max, TNT Sports Ultimate
Northampton Saints boss set for England talks after Alex Mitchell injury: ‘We can do better’
Newcastle Red Bulls v Sale Sharks
Prediction: Sale by 20
Newcastle Red Bulls: 15 Ethan Grayson, 14 Christian Wade, 13 Alex Hearle, 12 Sammy Arnold, 11 Harrison Obatoyinbo, 10 Brett Connon, 9 Simón Benítez Cruz, 8 Amanaki Mafi, 7 Tom Christie, 6 Ollie Leatherbarrow, 5 Adam Scott, 4 Jamie Hodgson, 3 Richard Palframan, 2 George McGuigan (c), 1 Connor Hancock
Replacements: 16 Ollie Fletcher, 17 Jamie Clark, 18 Murray McCallum, 19 Tim Cardall, 20 Freddie Lockwood, 21 James Elliott, 22 Ben Healy, 23 Cameron Hutchison
Sale Sharks: 15 Joe Carpenter, 14 Tom Roebuck, 13 Luke James, 12 Rekeiti Ma’asi-White, 11 Arron Reed, 10 George Ford, 9 Gus Warr, 8 Reuben Logan, 7 Seb Kelly, 6 Sam Dugdale, 5 Ben Bamber, 4 Ernst van Rhyn (c), 3 James Harper, 2 Alfie Longstaff, 1 Asher Opoku-Fordjour
Replacements: 16 Wills Austin, 17 Ralph McEachran, 18 Patreece Bell, 19 Hyron Andrews, 20 Tristan Woodman, 21 Raffi Quirke, 22 Ollie Davies, 23 Tom O’Flaherty
Venue: Kingston Park
Kick-off: 19:45 BST
Referee: Christophe Ridley
Assistant Referees: Jamie Parr, Henry Pearson
TMO: Hamish Smales
How to watch: Live on TNT Sports Extra & HBO Max
Sunday
England hopeful nearing return in welcome boost for Steve Borthwick
Leicester Tigers v Exeter Chiefs
Prediction: Leicester by 7
Leicester Tigers: 15 George Pearson, 14 Adam Radwan, 13 Will Wand, 12 Orlando Bailey, 11 Ollie Hassell-Collins, 10 Charlie Titcombe, 9 Jack van Poortvliet, 8 Joaquin Moro, 7 Tommy Reffell, 6 Hanro Liebenberg, 5 Ollie Chessum (c), 4 George Martin, 3 Joe Heyes, 2 Jamie Blamire, 1 Nicky Smith
Replacements: 16 Charlie Clare, 17 Archie van der Flier, 18 Will Hurd, 19 Cameron Henderson, 20 Hamish Watson, 21 Olly Cracknell, 22 Tom Whiteley, 23 Solomone Kata
Exeter Chiefs: 15 Olly Woodburn, 14 Immanuel Feyi-Waboso, 13 Henry Slade, 12 Len Ikitau, 11 Campbell Ridl, 10 Harvey Skinner, 9 Stephen Varney, 8 Greg Fisilau, 7 Ethan Roots, 6 Tom Hooper, 5 Andrea Zambonin, 4 Dafydd Jenkins (c), 3 Josh Iosefa-Scott, 2 Max Norey, 1 Scott Sio
Replacements: 16 Joseph Dweba, 17 Ethan Burger, 18 Bachuki Tchumbadze, 19 Rusi Tuima, 20 Christ Tshiunza, 21 Tom Cairns, 22 Zack Wimbush, 23 Paul Brown-Bampoe
Venue: Mattioli Woods Welford Road
Kick-off: 15:30 BST
Referee: Anthony Woodthorpe
Assistant Referees: Ian Tempest, Jamie Leahy
TMO: David Rose
How to watch: Live on TNT Sports 1, HBO Max, TNT Sports Ultimate
READ MORE: Alex Mitchell OUT? Ranking seven England scrum-half options as Northampton Saints ‘proper job’ injury leaves Steve Borthwick with nervous wait
